Quantitative myocardial contrast echocardiography during pharmacological stress for diagnosis of coronary artery disease: a systematic review and meta-analysis of diagnostic accuracy studies
European Journal of Echocardiography 2009 10(7):813-825
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Existing data support a moderate diagnostic accuracy of quantitative MCE in the detection of CAD in patients with known or suspected CAD. However, standardization of the methods used for conduct, analysis, interpretation, and reporting of those measures is needed to facilitate clinical implementation of the quantitative MCE technique. A large multicentre study of sufficient sample size to provide valid and reliable cut-offs, composed of a broder spectrum of patients with acute and chronic CAD and using standardized protocols for imaging, data analysis, and interpretation, would be of great benefit for optimized clinical application of this technique in order to minimize the potential for heterogeneity as observed in the evaluated studies.
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Alguns métodos demoram para amadurecer. Demoram tanto que dá até sono...
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