segunda-feira, abril 25, 2011

Dobutamina para pacientes abaixo de 60 anos.



Does the prognostic value of dobutamine stress echocardiography differ among different age groups?
American Heart Journal
Issue: Volume 161(4), April 2011, p 740–745
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Methods: We studied 6,655 consecutive patients referred for DSE. Patients were divided into 3 age groups: (1) <60 years (n = 1,389), (2) 60 to 74 years (n = 2,978), and (3) >=75 years (n = 2,288). Mean follow-up was 5.5 ± 2.8 years. End points included all-cause mortality and cardiac events, including myocardial infarction and late (>3 months) coronary revascularization.
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Conclusions: Dobutamine stress echocardiography provided independent information predictive of cardiac events among all age groups and death in patients >=60 years. However, among patients <60 years, stress-induced echocardiographic abnormalities were not independently associated with mortality. Comorbidities, which have precluded exercise testing, may be most relevant in predicting mortality in patients <60 years undergoing DSE. . Interessante notar o valor preditivo do stress com dobutamina em indivíduos abaixo de 60 anos. Parece que o stress farmacológico seria mesmo eficiente em faixas etárias acima.

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