quinta-feira, março 12, 2009
Jogo dos 7 erros.
Prognostic utility of 64-slice computed tomography in patients with suspected but no documented coronary artery disease
European heart jounal Volume 30(3), February 2009, pp 362-37
1-This was an observational retrospective single-centre study where 227 consecutive subjects.
2-Initially, 720 patients who underwent MSCT in that time frame were screened. Patients were excluded if they had the following history: evidence of prior significant CAD (determined as chart documented >30% stenosis in any vessel on prior cardiac catheterization, prior myocardial infarction (MI), prior percutaneous intervention, prior coronary artery bypass grafting, emergent presentation with abnormal cardiac enzymes/dynamic ischaemic electrocardiographic changes, n=361) or non-coronary indications for MSCT (n=113)
3- International patients with no social security numbers (n=19), in whom follow-up could not be ascertained, were excluded from the analysis
4- To ascertain follow-up information and screen for occurrence of clinical events, electronic medical records, including clinic visits and telephone interviews, were reviewed.
5- At the time of this study, we routinely used intravenous metoprolol at 5 mg increments every 5 min (up to 30 mg) to bring the heart rate down to 65 beats.
6- Individuals with significant arrhythmia (atrial fibrillation and frequent premature beats) or rapid heart rate (>90 b.p.m.), and contraindications to beta-blockade/calcium channel blockade, were not imaged.
7- Kaplan–Meier analysis demonstrating freedom from major adverse cardiac events in two groups, separated on the basis of the presence or absence of proximal atherosclerotic plaque (log-rank statistic P-value=0.002). MACE, major adverse cardiac events.